CATSPER3

Across TCGA pan-cancer cohorts, CATSPER3 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CATSPER3 data layer compared with 7 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher CATSPER3 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CATSPER3 expression acts as an unfavorable survival marker, although some lineages such as MESO and KIRP show a favorable association.

MESO, STAD, and LUAD are the cancer types where CATSPER3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.499	0.275	<.001	120	view →
STAD	OS	Tertile	III,IV	0.504	0.727	.001	77	view →
LUAD	OS	Median	III,IV	0.498	0.769	.005	49	view →
KIRP	DFS	Median	III,IV	0.914	0.391	.008	38	view →
PAAD	DFS	Median	All	0.372	0.177	.002	24	view →
PRAD	DFS	Tertile	All	0.744	0.904	<.001	18	view →
OV	DFS	Tertile	II,III,IV	0.483	0.611	.005	16	view →
SKCM	OS	Quartile	IV	0.761	0.248	.002	16	view →
ACC	DFS	Tertile	IV	0.632	0.108	.001	12	view →
HNSC	DFS	Tertile	All	0.754	0.665	.020	12	view →
LIHC	DFS	Quartile	All	0.466	0.620	.005	12	view →
UVM	OS	Tertile	II,III,IV	0.527	0.741	.030	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CATSPER3–MESO (OS)

Open the MESO breakdown →