calcium/calmodulin dependent protein kinase II inhibitor 2Genealiases: CAM-KIIN · CAMKIIN
Q-omics provides the consensus-scored CAMK2N2 profile across patient tissues and cancer cell-line models. CAMK2N2 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, CAMK2N2 is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, CAMK2N2 RNA expression shows 18,601 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight MESO, HNSC, and LSCC as cancer lineages where CAMK2N2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CAMK2N2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CAMK2N2 survival associations across molecular data types. CAMK2N2 RNA expression shows survival associations in the most cancer types (20), followed by mutation status (1) and mass-spec protein abundance (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CAMK2N2 RNA expression–survival associations across cancer types. High CAMK2N2 expression shows unfavorable associations in MESO, ACC, KIRC, KIRP and BLCA, but favorable associations in CESC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for CAMK2N2 RNA expression.
This table summarizes CAMK2N2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for CAMK2N2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CAMK2N2 shows higher tumor expression in HNSC, KIRC, THCA, BLCA, LIHC and KIRP. The HNSC box plot shows higher CAMK2N2 RNA expression in tumor versus normal tissue (log2 FC = +1.523, t-test p < 0.001).
This table shows molecular features associated with CAMK2N2 in patient tissues and cancer cell lines. In patient samples, CAMK2N2 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set. In cancer cell lines, CAMK2N2 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT, while CRISPR and shRNA rows add functional-dependency signals in OVARY and LUNG_SCLC.
