CAMK2N2

Across TCGA pan-cancer cohorts, CAMK2N2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CAMK2N2 data layer compared with 1 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher CAMK2N2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CAMK2N2 expression acts as an unfavorable survival marker, although some lineages such as CESC and LGG show a favorable association.

MESO, ACC, and KIRC are the cancer types where CAMK2N2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	All	0.269	0.456	<.001	119	view →
ACC	DFS	Median	All	0.225	0.700	<.001	102	view →
KIRC	OS	Tertile	All	0.542	0.694	<.001	72	view →
KIRP	DFS	Quartile	All	0.714	0.940	<.001	62	view →
BLCA	OS	Median	II,III,IV	0.327	0.552	.002	57	view →
CESC	DFS	Tertile	All	0.621	0.373	.001	52	view →
LUAD	OS	Median	All	0.623	0.746	.003	43	view →
KICH	DFS	Median	III,IV	0.373	1.000	.008	36	view →
UCS	OS	Tertile	II,III,IV	0.398	0.769	.016	28	view →
LGG	DFS	Median	All	0.878	0.786	<.001	27	view →
SARC	DFS	Quartile	All	0.495	0.698	<.001	20	view →
PRAD	DFS	Quartile	All	0.649	0.912	<.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CAMK2N2–MESO (DFS)

Open the MESO breakdown →