CACNA1C-IT2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CACNA1C-IT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,119 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNA1C-IT2-associated proteins across cancer lineages are ITSN1, PDLIM7, and WDR47_S312. Each is linked with CACNA1C-IT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CACNA1C-IT2-to-partner and partner-to-CACNA1C-IT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA1C-IT2 versus ITSN1 in GBM, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1C-IT2→partner) and Y-score (partner→CACNA1C-IT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMITSN1 →+0.274+0.412<.001.00534
UCECPDLIM7 →+0.768+0.633<.001<.00134
OVWDR47_S312 →+0.888+0.078.007.00834
UCECTPM2 →+1.071+0.627<.001<.00134
UCECCSRP1 →+0.882+0.611<.001<.00134
UCECRASGRP2_S576 →+0.638+0.896<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,119 associations by consensus.

CACNA1C-IT2 vs ITSN1 — GBM

Per-sample scatter of CACNA1C-IT2 vs ITSN1 in GBM (Pearson r = 0.30).

Explore this scatter interactively →

Exploration