CA5A

Across TCGA patient cohorts, CA5A mutation is significantly associated with the RNA expression of many other genes, with 729 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CA5A-associated genes across cancer lineages are RNU6-166P, LINC01817, and LINC01880. Each is linked with CA5A in more than 2 cancer types. Because this analysis shows association rather than direction, both CA5A-to-partner and partner-to-CA5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-166P grouped by CA5A-low versus CA5A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA5A→partner) and Y-score (partner→CA5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-166P →	+0.343	+7.640	<.001	.009	3	3
SKCM	LINC01817 →	+0.048	+4.469	<.001	.006	3	3
CESC	LINC01880 →	+0.164	+5.201	<.001	.007	3	2
BRCA	MIR4498 →	+0.522	+8.055	<.001	.007	3	2
BLCA	RNU6-225P →	+0.593	+7.640	<.001	.009	3	2
SKCM	RPL21P121 →	+0.162	+3.884	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 729 associations by consensus.

RNU6-166P by CA5A expression — BLCA

Explore this box plot interactively →