CA5A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CA5A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CA5A-associated genes across cancer lineages are MS4A13. Each is linked with CA5A in more than 1 cancer types. Because this analysis shows association rather than direction, both CA5A-to-partner and partner-to-CA5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A13 grouped by CA5A-low versus CA5A-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA5A→partner) and Y-score (partner→CA5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCMS4A13 →+0.035+4.643<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MS4A13 by CA5A expression — LUNG_SCLC

Box plot of MS4A13 in CA5A-low vs CA5A-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration