C9orf62

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C9orf62 mutation is significantly associated with the RNA expression of many other genes, with 137 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C9orf62-associated genes across cancer lineages are LINC01050, MIR6766, and RN7SL197P. Each is linked with C9orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf62-to-partner and partner-to-C9orf62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01050 grouped by C9orf62-low versus C9orf62-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf62→partner) and Y-score (partner→C9orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLINC01050 →+0.223+2.702.005.00431
UCECMIR6766 →+0.397+3.136<.001.00831
UCECRN7SL197P →+0.251+3.599<.001<.00131
UCECMIR7976 →+0.574+2.868<.001.00631
UCECMIR6783 →+0.650+2.517.001.00831
UCECSPDYE9 →+0.006+4.049<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 137 associations by consensus.

LINC01050 by C9orf62 expression — UCEC

Box plot of LINC01050 in C9orf62-low vs C9orf62-high samples in UCEC.

Explore this box plot interactively →

Exploration