C9orf62

Across TCGA pan-cancer cohorts, C9orf62 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of C9orf62’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where C9orf62 RNA is repressed in tumor relative to normal tissue. In most cancer types C9orf62 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC and THCA are the cancer types where C9orf62 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C9orf62 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.020	<.001	5	view →
THCA	All	All	+0.028	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

C9orf62–LUSC

Open the LUSC breakdown →