C8orf87

Across TCGA cell cohorts, C8orf87 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C8orf87-associated genes across cancer lineages are OR52N2, LRRC74A, and SERPINA7. Each is linked with C8orf87 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf87-to-partner and partner-to-C8orf87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52N2 grouped by C8orf87-low versus C8orf87-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf87→partner) and Y-score (partner→C8orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR52N2 →	+0.100	+4.044	<.001	.009	3	1
LUNG_NSCLC_LUAD	LRRC74A →	+0.016	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	SERPINA7 →	+0.013	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	SCN10A →	+0.006	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR6M1 →	+0.075	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	CXorf51A →	+0.083	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR52N2 by C8orf87 expression — LUNG_SCLC

Explore this box plot interactively →