C8orf87

Across TCGA pan-cancer cohorts, C8orf87 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of C8orf87’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where C8orf87 RNA is repressed in tumor relative to normal tissue. In most cancer types C8orf87 is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

LUSC, KICH, and BRCA are the cancer types where C8orf87 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C8orf87 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.104	<.001	5	view →
KICH	All	All	−0.115	.006	3	view →
BRCA	Female	All	+0.185	.021	2	view →
COAD	All	II,III,IV	+0.084	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

C8orf87–LUSC

Open the LUSC breakdown →