Across TCGA patient cohorts, C6orf136 mutation is significantly associated with the RNA expression of many other genes, with 145 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf136-associated genes across cancer lineages are CYCSP27, MIR3135A, and RNU6-918P. Each is linked with C6orf136 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf136-to-partner and partner-to-C6orf136 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf136→partner) and Y-score (partner→C6orf136) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CYCSP27 →	+0.173	+4.799	.002	.003	3	2
UCEC	MIR3135A →	+0.432	+2.868	.002	.006	3	2
UCEC	RNU6-918P →	+0.525	+3.198	<.001	.007	3	2
BLCA	RN7SL104P →	+0.265	+5.320	<.001	.001	3	2
BLCA	A2ML1-AS2 →	+0.197	+5.213	<.001	.001	3	1
BLCA	LSM6P2 →	+0.365	+5.017	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

Exploration

C6orf136 survival (RNA) · tumor vs normal (RNA) · all C6orf136 data types