C5orf64

Across TCGA patient cohorts, C5orf64 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf64-associated genes across cancer lineages are RNU6-6P, SNX3P1Y, and RNU6-392P. Each is linked with C5orf64 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf64-to-partner and partner-to-C5orf64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-6P grouped by C5orf64-low versus C5orf64-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf64→partner) and Y-score (partner→C5orf64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-6P →	+0.762	+3.034	<.001	.003	3	1
UCEC	SNX3P1Y →	+0.199	+5.671	<.001	<.001	3	1
SKCM	RNU6-392P →	+0.288	+7.816	<.001	.008	3	1
SKCM	SNORD114-12 →	+0.367	+7.816	<.001	.008	3	1
SKCM	OR51G1 →	+0.044	+7.816	<.001	.008	3	1
SKCM	RNU6-1291P →	+0.283	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

RNU6-6P by C5orf64 expression — UCEC

Explore this box plot interactively →