C3orf85

Across TCGA patient cohorts, C3orf85 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C3orf85-associated genes across cancer lineages are NFYAP1, SLC25A5P9, and FAM8A2P. Each is linked with C3orf85 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf85-to-partner and partner-to-C3orf85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NFYAP1 grouped by C3orf85-low versus C3orf85-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf85→partner) and Y-score (partner→C3orf85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	NFYAP1 →	+0.239	+5.010	<.001	.009	3	1
CESC	SLC25A5P9 →	+0.069	+5.418	<.001	.005	3	1
CESC	FAM8A2P →	+0.056	+5.539	<.001	.004	3	1
CESC	LINC02713 →	+0.056	+5.306	<.001	.006	3	1
CESC	HNRNPDLP4 →	+0.308	+5.418	<.001	.005	3	1
UCEC	RGPD5 →	+0.010	+4.220	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

NFYAP1 by C3orf85 expression — CESC

Explore this box plot interactively →