C3orf85

Across TCGA pan-cancer cohorts, C3orf85 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated C3orf85 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher C3orf85 RNA is associated with better overall survival. In most high-consensus cancer types, elevated C3orf85 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LIHC show a favorable association.

KIRC, UVM, and LIHC are the cancer types where C3orf85 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.709	0.548	<.001	132	view →
UVM	DFS	Tertile	All	0.152	0.792	<.001	45	view →
LIHC	DFS	Quartile	All	0.392	0.193	.002	41	view →
DLBC	OS	Tertile	III,IV	0.154	0.735	.010	40	view →
LUAD	DFS	Tertile	III,IV	0.379	0.689	.019	36	view →
BRCA	DFS	Tertile	IV	0.175	0.730	.005	36	view →
CHOL	OS	Quartile	II,III,IV	0.111	0.785	<.001	27	view →
KIRP	OS	Median	II,III,IV	0.881	0.650	.013	27	view →
BLCA	DFS	Tertile	All	0.130	0.358	.016	21	view →
PAAD	DFS	Median	III,IV	0.370	0.853	.010	19	view →
ESCA	OS	Median	All	0.659	1.000	.020	18	view →
PCPG	OS	Tertile	All	0.834	0.974	.035	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

C3orf85–KIRC (OS)

Open the KIRC breakdown →