C2orf49

Across TCGA patient cohorts, C2orf49 mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. COAD shows the largest number of these associations.

The most reproducible C2orf49-associated genes across cancer lineages are RNU6-751P, RN7SL83P, and RNU6ATAC29P. Each is linked with C2orf49 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf49-to-partner and partner-to-C2orf49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-751P grouped by C2orf49-low versus C2orf49-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf49→partner) and Y-score (partner→C2orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-751P →	+0.427	+7.930	<.001	.008	3	2
COAD	RN7SL83P →	+0.695	+6.392	<.001	.001	3	2
BLCA	RNU6ATAC29P →	+0.445	+5.038	<.001	.009	3	1
BLCA	MIR1252 →	+0.497	+4.973	<.001	.009	3	1
BLCA	RNU6-733P →	+0.630	+5.411	<.001	.005	3	1
BLCA	SFPQP1 →	+0.040	+5.329	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

RNU6-751P by C2orf49 expression — LUAD

Explore this box plot interactively →