C20orf197

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C20orf197 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C20orf197-associated genes across cancer lineages are RNA5SP369, RN7SL248P, and LINC01519. Each is linked with C20orf197 in more than 1 cancer types. Because this analysis shows association rather than direction, both C20orf197-to-partner and partner-to-C20orf197 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP369 grouped by C20orf197-low versus C20orf197-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf197→partner) and Y-score (partner→C20orf197) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP369 →+0.710+3.193<.001.00432
UCECRN7SL248P →+0.225+5.722<.001<.00131
SKCMLINC01519 →+0.016+4.385.002.00831
SKCMPSMC1P6 →+0.020+4.495<.001.00731
SKCMMARK2P17 →+0.234+3.933<.001.00731
SKCMEGFLAM-AS1 →+0.114+4.118.003.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

RNA5SP369 by C20orf197 expression — UCEC

Box plot of RNA5SP369 in C20orf197-low vs C20orf197-high samples in UCEC.

Explore this box plot interactively →

Exploration