C20orf197

Across TCGA pan-cancer cohorts, C20orf197 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated C20orf197 data layer compared with 1 for mutation status.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher C20orf197 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated C20orf197 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

ESCA, LGG, and LUAD are the cancer types where C20orf197 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Tertile	III,IV	0.658	0.318	.001	74	view →
LGG	DFS	Median	All	0.276	0.497	<.001	50	view →
LUAD	OS	Quartile	All	0.549	0.278	<.001	44	view →
ACC	DFS	Median	All	0.751	0.418	<.001	43	view →
SKCM	DFS	Median	II,III,IV	0.301	0.151	<.001	38	view →
SCLC	OS	Quartile	II,III,IV	0.194	1.000	.024	16	view →
LUSC	OS	Median	II,III,IV	0.814	0.650	.003	15	view →
MESO	DFS	Tertile	IV	0.545	0.147	.008	15	view →
STAD	DFS	Quartile	IV	0.081	0.453	.025	14	view →
LAML	DFS	Median	All	0.466	0.692	.021	10	view →
SARC	OS	Median	All	0.795	0.689	.014	8	view →
CESC	OS	Median	II,III,IV	0.897	0.744	.017	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

C20orf197–ESCA (DFS)

Open the ESCA breakdown →