Across TCGA patient cohorts, C1orf68 mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf68-associated genes across cancer lineages are RPL23AP90, MIR6075, and MIR6747. Each is linked with C1orf68 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf68-to-partner and partner-to-C1orf68 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf68→partner) and Y-score (partner→C1orf68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL23AP90 →	+0.502	+3.226	<.001	.002	3	1
UCEC	MIR6075 →	+0.378	+3.316	.001	.002	3	1
UCEC	MIR6747 →	+1.052	+2.620	<.001	.008	3	1
UCEC	IGHV1OR21-1 →	+0.762	+3.800	.006	.001	3	1
UCEC	SSTR5 →	+0.763	+3.093	<.001	.003	3	1
UCEC	OR6K6 →	+0.091	+3.358	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration

C1orf68 survival (RNA) · tumor vs normal (RNA) · all C1orf68 data types