C1orf35

Across TCGA patient cohorts, C1orf35 mutation is significantly associated with the RNA expression of many other genes, with 125 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf35-associated genes across cancer lineages are OR10AA1P, RN7SL62P, and FTMT. Each is linked with C1orf35 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf35-to-partner and partner-to-C1orf35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10AA1P grouped by C1orf35-low versus C1orf35-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf35→partner) and Y-score (partner→C1orf35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR10AA1P →	+0.195	+5.329	<.001	.006	3	2
CESC	RN7SL62P →	+0.152	+5.812	<.001	.003	3	2
UCEC	FTMT →	+0.442	+3.019	<.001	.001	3	2
BLCA	LINC02665 →	+0.132	+6.444	<.001	.001	3	2
HNSC	UBTFL3 →	+0.079	+7.954	<.001	.008	3	1
UCEC	HLCS →	+0.886	+3.201	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 125 associations by consensus.

OR10AA1P by C1orf35 expression — BLCA

Explore this box plot interactively →