C1QTNF1

Across TCGA patient cohorts, C1QTNF1 mutation is significantly associated with the RNA expression of many other genes, with 2,100 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1QTNF1-associated genes across cancer lineages are RNA5SP334, RN7SL708P, and LINC02559. Each is linked with C1QTNF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF1-to-partner and partner-to-C1QTNF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP334 grouped by C1QTNF1-low versus C1QTNF1-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF1→partner) and Y-score (partner→C1QTNF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNA5SP334 →	+0.357	+6.135	<.001	.002	3	2
BLCA	RN7SL708P →	+0.106	+3.691	<.001	.004	3	2
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	2
COAD	RNU6-128P →	+0.958	+4.418	<.001	.008	3	2
COAD	RN7SL683P →	+0.798	+4.173	<.001	.003	3	2
UCEC	RNVU1-28 →	+0.549	+1.528	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,100 associations by consensus.

RNA5SP334 by C1QTNF1 expression — LGG

Explore this box plot interactively →