C1QTNF1

Across TCGA pan-cancer cohorts, C1QTNF1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of C1QTNF1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where C1QTNF1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C1QTNF1 is over-expressed in tumor, although a few such as KICH and LIHC show the opposite, repressed pattern.

COAD, HNSC, and KICH are the cancer types where C1QTNF1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C1QTNF1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	III,IV	+1.562	<.001	11	view →
HNSC	All	III,IV	+1.186	<.001	11	view →
KICH	Male	II,III,IV	−2.657	<.001	10	view →
KIRC	Male	All	+0.891	<.001	8	view →
LIHC	Male	All	−1.639	<.001	7	view →
UCEC	All	III,IV	−3.032	<.001	6	view →
BRCA	All	II,III,IV	−1.376	<.001	6	view →
CHOL	All	II,III,IV	−1.920	.033	2	view →
PRAD	All	All	−1.336	<.001	2	view →
KIRP	Female	II,III,IV	−1.286	.020	2	view →
LUAD	All	All	−0.468	.006	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

C1QTNF1–COAD

Open the COAD breakdown →