C19orf44

Across TCGA cell cohorts, C19orf44 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C19orf44-associated genes across cancer lineages are AVPR1B, SYT10, and OR1L3. Each is linked with C19orf44 in more than 1 cancer types. Because this analysis shows association rather than direction, both C19orf44-to-partner and partner-to-C19orf44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVPR1B grouped by C19orf44-low versus C19orf44-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf44→partner) and Y-score (partner→C19orf44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	AVPR1B →	+0.009	+4.415	<.001	.007	3	2
SKIN	SYT10 →	+0.492	+5.217	<.001	<.001	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
SKIN	KRTAP2-1 →	+0.193	+4.415	<.001	.007	3	1
SKIN	SKOR2 →	+0.326	+4.095	<.001	.009	3	1
LARGE_INTESTINE	PHOX2B →	+0.038	+4.362	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

AVPR1B by C19orf44 expression — SKIN

Explore this box plot interactively →