C19orf44

Across TCGA pan-cancer cohorts, C19orf44 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of C19orf44’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where C19orf44 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C19orf44 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, THCA, and COAD are the cancer types where C19orf44 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C19orf44 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.466	<.001	11	view →
THCA	Male	III,IV	−0.747	<.001	10	view →
COAD	Female	All	+0.484	<.001	10	view →
KICH	Female	All	−1.528	<.001	8	view →
LIHC	Female	III,IV	+1.038	<.001	8	view →
CHOL	Female	All	+2.376	<.001	3	view →
HNSC	All	III,IV	+0.274	.033	3	view →
KIRP	All	IV	+0.842	.026	2	view →
UCEC	All	All	−0.382	.012	2	view →
BLCA	Male	IV	−1.002	.007	1	view →
ESCA	All	All	+0.503	.047	1	view →
LUSC	Male	All	−0.217	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

C19orf44–KIRC

Open the KIRC breakdown →