C14orf28

Across TCGA patient cohorts, C14orf28 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,316 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C14orf28-associated proteins across cancer lineages are NEK9, RAI14, and RPL6. Each is linked with C14orf28 in more than 5 cancer types. Because this analysis shows association rather than direction, both C14orf28-to-partner and partner-to-C14orf28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C14orf28 versus NEK9 in LUAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf28→partner) and Y-score (partner→C14orf28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NEK9 →	+0.277	+0.401	<.001	.003	3	6
OV	RAI14 →	+0.374	+0.488	.001	<.001	3	6
CCRCC	RPL6 →	-0.437	-0.373	<.001	<.001	3	6
GBM	RPL7 →	-0.364	-0.349	<.001	<.001	3	6
OV	FKBP3 →	+0.392	+0.407	<.001	.001	3	6
BRCA	ILK →	+0.352	+0.482	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,316 associations by consensus.

C14orf28 vs NEK9 — LUAD

Explore this scatter interactively →