C12orf60

Across TCGA patient cohorts, C12orf60 protein abundance is significantly associated with the RNA expression of many other genes, with 330 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C12orf60-associated genes across cancer lineages are MAP2K3, RIN3, and APEX1. Each is linked with C12orf60 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf60-to-partner and partner-to-C12orf60 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf60 versus MAP2K3 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf60→partner) and Y-score (partner→C12orf60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP2K3 →	-0.910	-0.848	.001	.006	3	2
LSCC	RIN3 →	-0.953	-1.024	.002	.009	3	1
LSCC	APEX1 →	+0.706	+1.028	.004	.006	3	1
LSCC	STS →	-1.018	-0.738	.006	.005	3	1
LSCC	STAB1 →	-1.706	-0.896	.006	.009	3	1
LSCC	LILRB1 →	-1.350	-0.941	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 330 associations by consensus.

C12orf60 vs MAP2K3 — LSCC

Explore this scatter interactively →