C12orf60

Across TCGA cell cohorts, C12orf60 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible C12orf60-associated genes across cancer lineages are SCT, SPAM1, and VSIG4. Each is linked with C12orf60 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf60-to-partner and partner-to-C12orf60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCT grouped by C12orf60-low versus C12orf60-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf60→partner) and Y-score (partner→C12orf60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SCT →	+0.241	+4.017	<.001	.007	3	1
CNS	SPAM1 →	+0.006	+5.321	<.001	.005	3	1
CNS	VSIG4 →	+0.022	+4.981	<.001	.008	3	1
BLOOD_Lymphoma	OR6F1 →	+0.186	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	TEX26 →	+0.021	+4.867	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

SCT by C12orf60 expression — OESOPHAGUS

Explore this box plot interactively →