Q-omics provides the consensus-scored C11orf71 profile across patient tissues and cancer cell-line models. C11orf71 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, C11orf71 is differentially expressed in 11, with the highest sampling consensus in THCA. Additionally, C11orf71 RNA expression shows 19,267 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UCEC, THCA, and UVM as cancer lineages where C11orf71 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for C11orf71 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes C11orf71 survival associations across molecular data types. C11orf71 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible C11orf71 RNA expression–survival associations across cancer types. High C11orf71 expression shows unfavorable associations in UVM, but favorable associations in UCEC, KIRC, LUSC, MESO and OV. The UCEC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for C11orf71 RNA expression.
This table summarizes C11orf71 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for C11orf71. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C11orf71 shows lower tumor expression in THCA, KIRC, KIRP, KICH, LUAD and COAD. The THCA box plot shows higher C11orf71 RNA expression in normal versus tumor tissue (log2 FC = −0.638, t-test p < 0.001).
This table shows molecular features associated with C11orf71 in patient tissues and cancer cell lines. In patient samples, C11orf71 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, C11orf71 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BREAST, while CRISPR and shRNA rows add functional-dependency signals in BONE and UPPER_AERODIGESTIVE_TRACT.
