C11orf71

Across TCGA cell cohorts, C11orf71 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C11orf71-associated genes across cancer lineages are ZP2, GPR42, and ZIC3. Each is linked with C11orf71 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf71-to-partner and partner-to-C11orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZP2 grouped by C11orf71-low versus C11orf71-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf71→partner) and Y-score (partner→C11orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZP2 →	+0.179	+4.409	<.001	.005	3	1
BLOOD_Leukemia	GPR42 →	+0.026	+4.152	.004	.009	3	1
BLOOD_Leukemia	ZIC3 →	+0.019	+5.060	<.001	.001	3	1
BLOOD_Leukemia	KRTAP17-1 →	+0.695	+5.060	.007	.001	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

ZP2 by C11orf71 expression — BLOOD_Leukemia

Explore this box plot interactively →