C11orf71

Across TCGA patient cohorts, C11orf71 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf71-associated genes across cancer lineages are RNA5SP333, RNU6-821P, and MIR4493. Each is linked with C11orf71 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf71-to-partner and partner-to-C11orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP333 grouped by C11orf71-low versus C11orf71-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf71→partner) and Y-score (partner→C11orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP333 →	+0.423	+6.618	<.001	.001	3	1
BLCA	RNU6-821P →	+0.349	+5.497	<.001	.004	3	1
BRCA	MIR4493 →	+0.772	+8.055	<.001	.007	3	1
BRCA	RNA5SP472 →	+0.332	+7.731	<.001	.009	3	1
BRCA	RNU6-715P →	+0.618	+9.057	<.001	.003	3	1
BRCA	MTND1P1 →	+0.124	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

RNA5SP333 by C11orf71 expression — BLCA

Explore this box plot interactively →