C11orf71

Across TCGA cell cohorts, C11orf71 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,246 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible C11orf71-associated GO terms across cancer lineages are Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and Valine metabolic process. Each is linked with C11orf71 in more than 12 cancer types. Because this analysis shows association rather than direction, both C11orf71-to-partner and partner-to-C11orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway grouped by C11orf71-low versus C11orf71-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf71→partner) and Y-score (partner→C11orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.144	+1.225	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.137	+1.409	.001	.001	3	12
LIVER	Valine metabolic process →	+0.133	+0.742	.006	.009	3	10
LIVER	L-valine catabolic process →	+0.133	+0.742	.006	.009	3	10
CNS	COPII vesicle coating →	+0.084	+0.994	<.001	<.001	3	9
LUNG_SCLC	Intracellular protein transmembrane transport →	+0.095	+1.101	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,246 associations by consensus.

Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway by C11orf71 expression — LUNG_SCLC

Explore this box plot interactively →