C10orf88B

Across TCGA patient cohorts, C10orf88B mutation is significantly associated with the RNA expression of many other genes, with 74 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf88B-associated genes across cancer lineages are AQP7P3, RN7SL462P, and AQP7P2. Each is linked with C10orf88B in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf88B-to-partner and partner-to-C10orf88B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AQP7P3 grouped by C10orf88B-low versus C10orf88B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf88B→partner) and Y-score (partner→C10orf88B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AQP7P3 →	+0.069	+4.260	<.001	.007	3	1
SKCM	RN7SL462P →	+0.109	+7.816	<.001	.008	3	1
UCEC	AQP7P2 →	+0.335	+3.332	<.001	.004	3	1
UCEC	RNU6-451P →	+0.653	+3.386	<.001	.008	3	1
UCEC	RNA5SP393 →	+0.508	+3.766	<.001	.001	3	1
UCEC	RNU6-1155P →	+0.254	+5.738	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

AQP7P3 by C10orf88B expression — UCEC

Explore this box plot interactively →