Q-omics provides the consensus-scored RNU6-451P profile across patient tissues and cancer cell-line models. RNU6-451P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in TGCT. Additionally, RNU6-451P RNA expression shows 7,711 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight TGCT, and DLBC as cancer lineages where RNU6-451P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for RNU6-451P — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes RNU6-451P survival associations across molecular data types. RNU6-451P RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-451P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	TGCT (90)	view →

This table ranks reproducible RNU6-451P RNA expression–survival associations across cancer types. High RNU6-451P expression shows unfavorable associations in TGCT, THCA, LUSC and MESO, but favorable associations in ESCA and LUAD. The TGCT Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify TGCT as the clearest survival context for RNU6-451P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	All	0.804	0.975	<.001	90	view →
ESCA	DFS	Tertile	III,IV	0.682	0.252	.001	72	view →
THCA	OS	Tertile	III,IV	0.449	0.866	<.001	66	view →
LUSC	OS	Tertile	II,III,IV	0.521	0.750	.011	63	view →
MESO	OS	Tertile	III,IV	0.077	0.580	<.001	54	view →
LUAD	OS	Tertile	All	0.867	0.319	.010	54	view →

Pink = unfavorable, green = favorable. all 12 lineages →

RNU6-451P-TGCT (OS)

Kaplan–Meier survival curve for RNU6-451P RNA expression in TGCT: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-451P in patient tissues and cancer cell lines. In patient samples, RNU6-451P shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,711	DLBC (2855)	view →
Function (RNA)	6,439	STAD (5564)	view →