C10orf88B

Across TCGA pan-cancer cohorts, C10orf88B RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated C10orf88B data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher C10orf88B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C10orf88B expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.

KIRP, MESO, and UCS are the cancer types where C10orf88B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.477	0.688	<.001	123	view →
MESO	DFS	Median	All	0.271	0.454	<.001	114	view →
UCS	OS	Tertile	II,III,IV	0.743	0.199	.001	88	view →
ACC	OS	Median	All	0.420	0.836	<.001	65	view →
LIHC	DFS	Tertile	All	0.402	0.582	<.001	64	view →
KIRC	OS	Tertile	All	0.509	0.705	<.001	48	view →
THCA	DFS	Tertile	All	0.765	0.902	.001	43	view →
UCEC	DFS	Median	All	0.535	0.785	.002	30	view →
COAD	DFS	Quartile	II,III,IV	0.680	0.851	.004	22	view →
PCPG	OS	Tertile	All	0.775	1.000	.006	20	view →
LUAD	OS	Tertile	All	0.769	0.868	.002	19	view →
BLCA	OS	Quartile	III,IV	0.623	0.431	.014	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

C10orf88B–KIRP (DFS)

Open the KIRP breakdown →