C10orf71

Across TCGA patient cohorts, C10orf71 mutation is significantly associated with the RNA expression of many other genes, with 5,024 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf71-associated genes across cancer lineages are PMS2CL, ILRUN, and ZNF695. Each is linked with C10orf71 in more than 2 cancer types. Because this analysis shows association rather than direction, both C10orf71-to-partner and partner-to-C10orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PMS2CL grouped by C10orf71-low versus C10orf71-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf71→partner) and Y-score (partner→C10orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PMS2CL →	+0.307	+3.150	.002	<.001	3	3
SKCM	ILRUN →	+0.308	+1.006	<.001	.007	3	3
UCEC	ZNF695 →	+0.424	+1.895	.001	<.001	3	3
LUAD	MTATP6P17 →	+0.083	+2.980	<.001	.003	3	3
LUAD	SNRPGP20 →	+0.098	+4.301	<.001	.006	3	3
PAAD	MIR6780A →	+0.674	+4.392	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,024 associations by consensus.

PMS2CL by C10orf71 expression — UCEC

Explore this box plot interactively →