Q-omics provides the consensus-scored MIR6780A profile across patient tissues and cancer cell-line models. MIR6780A expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MIR6780A is differentially expressed in 2, with the highest sampling consensus in STAD. Additionally, MIR6780A RNA expression shows 5,050 significant pathway-activity associations, with the highest sampling consensus in KIRC. Together, these results highlight UVM, STAD, and KIRC as cancer lineages where MIR6780A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR6780A — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR6780A survival associations across molecular data types. MIR6780A RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR6780A RNA expression–survival associations across cancer types. High MIR6780A expression shows unfavorable associations in UVM, LUSC, LIHC, TGCT, COAD and ACC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for MIR6780A RNA expression.
This table summarizes MIR6780A tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in STAD for RNA.
This table ranks reproducible tumor–normal expression differences for MIR6780A. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR6780A shows higher tumor expression in STAD and COAD. The STAD box plot shows higher MIR6780A RNA expression in tumor versus normal tissue (log2 FC = +0.257, t-test p = .033).
This table shows molecular features associated with MIR6780A in patient tissues and cancer cell lines. In patient samples, MIR6780A shows the broadest associations at the RNA and protein expression levels, with KIRC recurring as the lineage with the largest associated feature set.
