MIR6780A

Across TCGA pan-cancer cohorts, MIR6780A RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MIR6780A data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR6780A RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR6780A expression acts as an unfavorable survival marker, although some lineages such as BRCA show a favorable association.

UVM, LUSC, and LIHC are the cancer types where MIR6780A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.150	0.772	<.001	126	view →
LUSC	OS	Tertile	III,IV	0.166	0.429	.001	102	view →
LIHC	DFS	Tertile	All	0.083	0.559	<.001	75	view →
TGCT	DFS	Tertile	III,IV	0.010	1.000	<.001	72	view →
COAD	OS	Tertile	All	0.598	0.813	.001	66	view →
ACC	OS	Tertile	All	0.269	0.845	<.001	39	view →
HNSC	OS	Tertile	II,III,IV	0.188	0.368	.018	33	view →
BRCA	OS	Tertile	All	0.836	0.547	.005	24	view →
KIRP	DFS	Tertile	All	0.730	0.875	.014	21	view →
LGG	OS	Tertile	All	0.187	0.486	<.001	12	view →
BLCA	DFS	Tertile	IV	0.147	0.475	.032	9	view →
SKCM	DFS	Tertile	IV	0.016	0.541	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MIR6780A–UVM (DFS)

Open the UVM breakdown →