C10orf71

Across TCGA pan-cancer cohorts, C10orf71 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated C10orf71 data layer compared with 7 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher C10orf71 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C10orf71 expression acts as an unfavorable survival marker, although some lineages such as ESCA and UCS show a favorable association.

THCA, LUSC, and ESCA are the cancer types where C10orf71 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	II,III,IV	0.882	0.985	<.001	72	view →
LUSC	OS	Tertile	IV	0.057	0.786	.008	43	view →
ESCA	OS	Median	II,III,IV	0.766	0.582	.009	35	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	27	view →
THYM	DFS	Quartile	All	0.666	0.945	.001	25	view →
HNSC	OS	Median	II,III,IV	0.697	0.813	.003	25	view →
UCS	DFS	Quartile	II,III,IV	0.690	0.163	.005	18	view →
BLCA	OS	Tertile	All	0.675	0.276	.010	18	view →
UVM	OS	Tertile	III,IV	0.270	0.718	.026	18	view →
SARC	OS	Median	All	0.379	0.633	<.001	16	view →
KIRP	OS	Tertile	All	0.791	0.928	.005	15	view →
COAD	DFS	Tertile	IV	0.304	0.552	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

C10orf71–THCA (OS)

Open the THCA breakdown →