BUD31

Across TCGA patient cohorts, BUD31 protein abundance is significantly associated with the RNA expression of many other genes, with 16,573 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BUD31-associated genes across cancer lineages are MCM7, DKC1, and DNAJC2. Each is linked with BUD31 in more than 9 cancer types. Because this analysis shows association rather than direction, both BUD31-to-partner and partner-to-BUD31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BUD31 versus MCM7 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BUD31→partner) and Y-score (partner→BUD31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MCM7 →	+1.337	+0.218	<.001	.001	3	10
LSCC	DKC1 →	+0.750	+0.274	<.001	<.001	3	8
HNSC	DNAJC2 →	+0.778	+0.349	<.001	<.001	3	7
HNSC	NUDT1 →	+0.770	+0.349	<.001	<.001	3	7
HNSC	CEP72 →	+0.942	+0.273	<.001	<.001	3	7
LSCC	GIGYF1 →	+0.559	+0.257	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,573 associations by consensus.

BUD31 vs MCM7 — UCEC

Explore this scatter interactively →