BUD31

Across TCGA pan-cancer cohorts, BUD31 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of BUD31’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where BUD31 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BUD31 is over-expressed in tumor.

KIRC, HNSC, and BLCA are the cancer types where BUD31 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BUD31 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.621	<.001	12	view →
HNSC	Male	III,IV	+1.078	<.001	11	view →
BLCA	All	All	+0.583	<.001	10	view →
LIHC	Female	II,III,IV	+1.191	<.001	9	view →
KIRP	All	II,III,IV	+0.608	<.001	9	view →
LUAD	All	All	+0.321	<.001	7	view →
STAD	All	II,III,IV	+0.580	<.001	6	view →
READ	Male	All	+0.506	.007	6	view →
BRCA	All	III,IV	+0.441	<.001	6	view →
CHOL	Male	All	+1.931	<.001	5	view →
LUSC	Male	All	+0.692	<.001	5	view →
COAD	Male	All	+0.539	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

BUD31–KIRC

Open the KIRC breakdown →