BUD31

Across TCGA pan-cancer cohorts, BUD31 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated BUD31 data layer compared with 4 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher BUD31 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BUD31 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CHOL show a favorable association.

KICH, ACC, and LIHC are the cancer types where BUD31 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.537	1.000	<.001	108	view →
ACC	DFS	Median	All	0.245	0.676	<.001	89	view →
LIHC	OS	Tertile	All	0.585	0.760	<.001	59	view →
KIRC	OS	Tertile	All	0.811	0.898	.002	52	view →
MESO	DFS	Median	All	0.275	0.438	.003	50	view →
LGG	OS	Median	All	0.722	0.894	<.001	44	view →
HNSC	DFS	Quartile	All	0.478	0.652	.001	41	view →
UCEC	DFS	Tertile	IV	0.193	0.599	.014	22	view →
CESC	OS	Quartile	IV	0.213	0.786	.009	18	view →
READ	DFS	Tertile	IV	0.254	0.831	.012	15	view →
SKCM	OS	Median	III,IV	0.834	0.576	.004	13	view →
SCLC	DFS	Tertile	II,III,IV	0.432	1.000	.006	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

BUD31–KICH (OS)

Open the KICH breakdown →