BUB1B

Across TCGA patient cohorts, BUB1B protein abundance is significantly associated with the RNA expression of many other genes, with 15,215 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BUB1B-associated genes across cancer lineages are FAM83D, SKA3, and CENPM. Each is linked with BUB1B in more than 6 cancer types. Because this analysis shows association rather than direction, both BUB1B-to-partner and partner-to-BUB1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BUB1B versus FAM83D in UCEC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BUB1B→partner) and Y-score (partner→BUB1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM83D →	+1.240	+0.686	<.001	<.001	3	7
UCEC	SKA3 →	+1.066	+0.670	<.001	<.001	3	7
UCEC	CENPM →	+1.458	+0.538	<.001	<.001	3	6
UCEC	MCM5 →	+1.118	+0.726	<.001	<.001	3	6
UCEC	CDKN3 →	+1.122	+0.653	<.001	<.001	3	6
LSCC	VRK1 →	+0.763	+0.454	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,215 associations by consensus.

BUB1B vs FAM83D — UCEC

Explore this scatter interactively →