Across TCGA patient cohorts, BLOC1S4 mutation is significantly associated with the RNA expression of many other genes, with 590 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BLOC1S4-associated genes across cancer lineages are RNU4-54P, RN7SKP272, and LIN7C. Each is linked with BLOC1S4 in more than 1 cancer types. Because this analysis shows association rather than direction, both BLOC1S4-to-partner and partner-to-BLOC1S4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S4→partner) and Y-score (partner→BLOC1S4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU4-54P →	+0.953	+4.070	<.001	.009	3	2
UCEC	RN7SKP272 →	+0.300	+2.601	.005	.003	3	2
UCEC	LIN7C →	+0.696	+3.480	.004	.002	3	1
UCEC	SAR1B →	+0.617	+3.459	.001	.005	3	1
UCEC	RAD17 →	+0.650	+3.459	<.001	.005	3	1
UCEC	GRAMD2B →	+0.791	+3.202	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 590 associations by consensus.

Exploration

BLOC1S4 survival (RNA) · tumor vs normal (RNA) · all BLOC1S4 data types