Q-omics provides the consensus-scored RNU4-54P profile across patient tissues and cancer cell-line models. RNU4-54P expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, RNU4-54P RNA expression shows 7,301 significant gene co-expression associations, with the highest sampling consensus in BRCA. Together, these results highlight HNSC, and BRCA as cancer lineages where RNU4-54P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU4-54P survival associations across molecular data types. RNU4-54P RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU4-54P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	HNSC (42)	view →

This table ranks reproducible RNU4-54P RNA expression–survival associations across cancer types. High RNU4-54P expression shows unfavorable associations in HNSC, MESO, OV, STAD, BLCA and SARC. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .011). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU4-54P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.354	0.665	.011	42	view →
MESO	OS	Tertile	III,IV	0.323	0.572	.042	36	view →
OV	OS	Tertile	IV	0.083	0.759	.027	36	view →
STAD	DFS	Tertile	All	0.296	0.533	.023	24	view →
BLCA	DFS	Tertile	III,IV	0.210	0.576	.011	18	view →
SARC	DFS	Tertile	All	0.089	0.591	.002	18	view →

Pink = unfavorable, green = favorable. all 9 lineages →

RNU4-54P-HNSC (OS)

Kaplan–Meier survival curve for RNU4-54P RNA expression in HNSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU4-54P in patient tissues and cancer cell lines. In patient samples, RNU4-54P shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,301	BRCA (3432)	view →
Function (RNA)	5,791	STAD (5370)	view →