RNU4-54P

Across TCGA pan-cancer cohorts, RNU4-54P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU4-54P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU4-54P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU4-54P expression acts as an unfavorable survival marker.

HNSC, OV, and MESO are the cancer types where RNU4-54P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.354	0.665	.011	42	view →
OV	OS	Tertile	IV	0.083	0.759	.027	36	view →
MESO	OS	Tertile	III,IV	0.323	0.572	.042	36	view →
STAD	DFS	Tertile	All	0.296	0.533	.023	24	view →
BLCA	DFS	Tertile	III,IV	0.210	0.576	.011	18	view →
SARC	DFS	Tertile	All	0.089	0.591	.002	18	view →
THYM	OS	Tertile	All	0.381	0.878	.017	12	view →
READ	DFS	Tertile	All	0.209	0.568	.038	9	view →
SKCM	OS	Tertile	II,III,IV	0.493	0.738	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU4-54P–HNSC (OS)

Open the HNSC breakdown →