BIVM-ERCC5

Across TCGA patient cohorts, BIVM-ERCC5 mutation is significantly associated with the RNA expression of many other genes, with 2,024 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BIVM-ERCC5-associated genes across cancer lineages are FAM74A6, SNRPBP1, and MTND5P27. Each is linked with BIVM-ERCC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both BIVM-ERCC5-to-partner and partner-to-BIVM-ERCC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM74A6 grouped by BIVM-ERCC5-low versus BIVM-ERCC5-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BIVM-ERCC5→partner) and Y-score (partner→BIVM-ERCC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM74A6 →	+0.018	+5.324	.003	.003	3	2
COAD	SNRPBP1 →	+0.364	+3.179	.001	.006	3	2
SKCM	MTND5P27 →	+0.014	+4.624	<.001	.005	3	2
STAD	RNU6-276P →	+0.616	+5.105	<.001	.008	3	2
UCEC	RN7SL248P →	+0.044	+2.783	<.001	.009	3	2
LUAD	RNU6-751P →	+0.427	+7.930	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,024 associations by consensus.

FAM74A6 by BIVM-ERCC5 expression — BRCA

Explore this box plot interactively →