BIVM-ERCC5

Across TCGA pan-cancer cohorts, BIVM-ERCC5 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated BIVM-ERCC5 data layer compared with 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher BIVM-ERCC5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BIVM-ERCC5 expression acts as an unfavorable survival marker, although some lineages such as MESO and KIRP show a favorable association.

COAD, STAD, and LUAD are the cancer types where BIVM-ERCC5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.224	0.590	<.001	51	view →
STAD	OS	Tertile	II,III,IV	0.536	0.701	.004	46	view →
LUAD	OS	Tertile	II,III,IV	0.111	0.280	.006	45	view →
THYM	OS	Tertile	All	0.836	0.985	.011	30	view →
SKCM	DFS	Tertile	III,IV	0.397	0.557	.012	22	view →
LAML	DFS	Tertile	All	0.193	0.494	.037	18	view →
CESC	OS	Tertile	IV	0.095	0.592	.004	18	view →
PAAD	DFS	Tertile	III,IV	0.275	0.794	.008	15	view →
MESO	DFS	Median	II,III,IV	0.323	0.186	.021	15	view →
KIRP	DFS	Tertile	IV	0.524	0.033	.010	12	view →
ACC	DFS	Tertile	II,III,IV	0.892	0.300	.007	9	view →
BLCA	DFS	Quartile	All	0.374	0.603	.032	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

BIVM-ERCC5–COAD (DFS)

Open the COAD breakdown →