BIVM-ERCC5

Across TCGA pan-cancer cohorts, BIVM-ERCC5 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of BIVM-ERCC5’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where BIVM-ERCC5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BIVM-ERCC5 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KIRC, KIRP, and KICH are the cancer types where BIVM-ERCC5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BIVM-ERCC5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.043	<.001	8	view →
KIRP	All	All	+0.061	.001	5	view →
KICH	All	II,III,IV	−0.021	<.001	5	view →
THCA	Female	All	−0.006	.009	2	view →
CHOL	All	All	+0.045	.029	1	view →
COAD	All	II,III,IV	+0.007	.039	1	view →
LIHC	Female	All	+0.006	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

BIVM-ERCC5–KIRC

Open the KIRC breakdown →