BET1-AS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BET1-AS1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BET1-AS1-associated genes across cancer lineages are MIR133B, SNORD115-9, and MIR1258. Each is linked with BET1-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BET1-AS1-to-partner and partner-to-BET1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR133B grouped by BET1-AS1-low versus BET1-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BET1-AS1→partner) and Y-score (partner→BET1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR133B →+0.356+8.066<.001.00731
UCECSNORD115-9 →+0.612+8.066<.001.00731
UCECMIR1258 →+0.509+8.066<.001.00731
UCECFAM243A →+0.069+8.066<.001.00731
UCECRNU7-95P →+0.562+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MIR133B by BET1-AS1 expression — UCEC

Box plot of MIR133B in BET1-AS1-low vs BET1-AS1-high samples in UCEC.

Explore this box plot interactively →

Exploration