BET1-AS1

Across TCGA pan-cancer cohorts, BET1-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated BET1-AS1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher BET1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated BET1-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and MESO show a favorable association.

SKCM, UVM, and MESO are the cancer types where BET1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	All	0.252	0.151	<.001	93	view →
UVM	DFS	Tertile	III,IV	0.282	0.807	.006	58	view →
MESO	OS	Tertile	II,III,IV	0.679	0.410	.001	48	view →
THYM	DFS	Quartile	II,III,IV	0.919	0.475	.002	48	view →
BLCA	OS	Median	All	0.525	0.346	<.001	43	view →
GBM	OS	Median	All	0.333	0.485	<.001	33	view →
HNSC	DFS	Tertile	IV	0.473	0.274	.006	27	view →
LUSC	DFS	Median	II,III,IV	0.529	0.687	.003	19	view →
THCA	DFS	Tertile	III,IV	0.870	0.990	.006	19	view →
ESCA	OS	Tertile	III,IV	0.691	0.367	.016	19	view →
KIRC	DFS	Median	III,IV	0.367	0.548	.012	14	view →
KIRP	DFS	Median	III,IV	0.159	0.547	.024	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

BET1-AS1–SKCM (DFS)

Open the SKCM breakdown →