BANF2

Across TCGA patient cohorts, BANF2 mutation is significantly associated with the RNA expression of many other genes, with 161 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible BANF2-associated genes across cancer lineages are RNU6-937P, RNU6-918P, and GSTA6P. Each is linked with BANF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BANF2-to-partner and partner-to-BANF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-937P grouped by BANF2-low versus BANF2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BANF2→partner) and Y-score (partner→BANF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-937P →	+0.297	+3.018	.004	.009	3	2
SKCM	RNU6-918P →	+0.307	+3.809	<.001	.003	3	2
SKCM	GSTA6P →	+0.070	+4.302	<.001	.007	3	2
UCEC	SLC25A51P1 →	+0.288	+4.661	<.001	.004	3	2
SKCM	RN7SL18P →	+0.236	+2.992	<.001	.009	3	2
SKCM	MTHFD2P6 →	+0.050	+3.178	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 161 associations by consensus.

RNU6-937P by BANF2 expression — SKCM

Explore this box plot interactively →